Prognostic value of the 6min walk test in bronchiolitis obliterans syndrome

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منابع مشابه

Prognostic value of bronchiolitis obliterans syndrome stage 0-p in single-lung transplant recipients.

RATIONALE Early diagnosis of bronchiolitis obliterans syndrome (BOS) is critical in understanding pathogenesis and devising therapeutic trials. Although potential-BOS stage (BOS 0-p), encompassing early changes in FEV(1) and forced expiratory flow, midexpiratory phase (FEF(25-75%)), has been proposed, there is a paucity of data validating its utility in single-lung transplantation. OBJECTIVE ...

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Azithromycin in posttransplant bronchiolitis obliterans syndrome.

Financial/nonfinancial disclosures: The authors have reported to CHEST the following conflicts of interest: Dr Verleden receives an annual research grant from GlaxoSmithKline (GSK) Belgium, and is holder of the GlaxoSmithKline Chair in Respiratory Pharmacology at the Katholieke Universiteit Leuven, Leuven, Belgium. The remaining authors have reported that no potential conflicts of interest exis...

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[Bronchiolitis obliterans associated with Stevens-Johnson syndrome].

Stevens-Johnson syndrome is a severe disease which is characterized by fever and mucocutaneous lesions. It has also been described as a small airway compromise in the form of bronchiolitis obliterans. We report a 22-year-old male patient with Stevens-Johnson syndrome due to antibiotic and antiepileptic drug treatment for brain abscess. After the improvement of mucocutaneous lesions, he went to ...

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Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome

Bronchiolitis obliterans syndrome (BOS), the main manifestation of chronic lung allograft dysfunction, leads to poor long-term survival after lung transplantation. Identifying predictors of BOS is essential to prevent the progression of dysfunction before irreversible damage occurs. By using a large set of 107 samples from lung recipients, we performed microarray gene expression profiling of wh...

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Bronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant.

The main change seen with BOS is scarring of the small airways of transplanted lung(s). This scarring leads to narrowing of the airways, limiting airflow with loss of lung function. Early after the onset of BOS, a person may not have any symptoms, but will develop breathlessness and chronic cough as BOS gets worse. There are different stages of BOS based on lung function results. Some people de...

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ژورنال

عنوان ژورنال: Respiratory Medicine

سال: 2009

ISSN: 0954-6111

DOI: 10.1016/j.rmed.2009.07.011